Metoclopramide (Reglan) Usage Can result in Permanent Tardive Dyskinesia

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The FDA has recently announced that drugs containing metoclopramide
must carry a boxed warning about the risk of tardive dyskinesia. Risk
of this condition is much higher with long-term usage and currently
the existing labels already carry an unboxed warning. The FDA
recommends that treatment last no longer than three months.

Often tardive dyskinesia will continue after stopping the drug and
rarely reverses. The FDA has said that manufacturers of the drugs that
contain metoclopramide are to also implement a risk mitigation
strategy that is to ensure patients will receive a medication guide
with each prescription which details the
adverse effects.

Metoclopramide-containing drugs include tablets, syrups and injections
which are used for short-term treatment of gastroesophageal reflux
disease in patients who haven't responded to other therapies.

[Vanny]

For those of you like myself that haven't a clue what TD stands for:

http://en.wikipedia.org/wiki/Tardive_dyskinesia

"Tardive dyskinesia is characterized by repetitive, involuntary, purposeless
movements. Features of the disorder may include grimacing, tongue
protrusion, lip smacking, puckering and pursing of the lips, and rapid eye
blinking. Rapid movements of the extremities may also occur. Impaired
movements of the fingers may also appear. For comparison, patients with
Parkinson's disease have difficulty moving, while patients with tardive
dyskinesia have difficulty not moving.
Other closely related neurological disorders have been recognized as
variants of tardive dyskinesia. Tardive akathisia involves painful feelings
of inner tension and anxiety and a compulsive drive to move the body. In the
extreme, the individual undergoes internal torture and can no longer sit
still. Tardive tourettism is a tic disorder that can closely mimic Tourette
Syndrome, sometimes to the point where the two can only be distinguished by
the details of their onsets..."

Post by ***@gmail.com |
The FDA has recently announced that drugs containing metoclopramide
must carry a boxed warning about the risk of tardive dyskinesia. Risk
of this condition is much higher with long-term usage and currently
the existing labels already carry an unboxed warning. The FDA
recommends that treatment last no longer than three months.
Often tardive dyskinesia will continue after stopping the drug and
rarely reverses. The FDA has said that manufacturers of the drugs that
contain metoclopramide are to also implement a risk mitigation
strategy that is to ensure patients will receive a medication guide
with each prescription which details the
adverse effects.
Metoclopramide-containing drugs include tablets, syrups and injections
which are used for short-term treatment of gastroesophageal reflux
disease in patients who haven't responded to other therapies.

[g***@yahoo.com]

Post by Vanny
http://en.wikipedia.org/wiki/Tardive_dyskinesia
"Tardive dyskinesia is characterized by repetitive, involuntary, purposeless
movements. Features of the disorder may include grimacing, tongue
protrusion, lip smacking, puckering and pursing of the lips, and rapid eye
blinking. Rapid movements of the extremities may also occur. Impaired
movements of the fingers may also appear. For comparison, patients with
Parkinson's disease have difficulty moving, while patients with tardive
dyskinesia have difficulty not moving.
Other closely related neurological disorders have been recognized as
variants of tardive dyskinesia. Tardive akathisia involves painful feelings
of inner tension and anxiety and a compulsive drive to move the body. In the
extreme, the individual undergoes internal torture and can no longer sit
still. Tardive tourettism is a tic disorder that can closely mimic Tourette
Syndrome, sometimes to the point where the two can only be distinguished by
the details of their onsets..."

Post by ***@gmail.com |
The FDA has recently announced that drugs containing metoclopramide
must carry a boxed warning about the risk of tardive dyskinesia. Risk
of this condition is much higher with long-term usage and currently
the existing labels already carry an unboxed warning. The FDA
recommends that treatment last no longer than three months.
Often tardive dyskinesia will continue after stopping the drug and
rarely reverses. The FDA has said that manufacturers of the drugs that
contain metoclopramide are to also implement a risk mitigation
strategy that is to ensure patients will receive a medication guide
with each prescription which details the
adverse effects.
Metoclopramide-containing drugs include tablets, syrups and injections
which are used for short-term treatment of gastroesophageal reflux
disease in patients who haven't responded to other therapies.- Hide quoted text -

- Show quoted text -

i became clinically depressed as a rersult of coming off this drug, i
believe it triggered it anyway

[g***@yahoo.com]

I was restless and couldnt sleep before my depression kicked in. i
feel much better now months later on anti depressants. by the way, it
wont return will it if i stay off metopramide?